Sleep apnoea, insulin resistance and diabetes: the first step is in the fat

Recent physiological/epidemiological evidence that SDB, in particular intermittent hypoxia, may increase production of inflammatory factors by adipose tissue - now recognised as a secretory organ - and subsequently impair liver and pancreatic function, contributing to development of T2D in SDB.

2. Sleep apnoea, insulin resistance and diabetes the first step is in the fat

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