This meta-analysis found that CPAP therapy is feasible in patients with early- and late-onset stroke complicated by SA, and CPAP may improve neurological outcomes. This study supported further research in this area. This meta-analysis included 14 RCTs that evaluated the effect of CPAP compared with that of usual treatment in patients with stroke or TIA with SA. Compared with the previous studies, our study added functional status as a primary outcome measure, and the results showed that...

To the best of our knowledge, this is the first prospective, observational study comparing risk for MACCEs in a revascularised CAD cohort with sleepy OSA receiving CPAP treatment with risk in patients without OSA. The results showed that the risk for MACCEs in revascularised CAD patients with sleepy OSA on CPAP was similar to that in CAD patients without OSA. In a multivariate analysis, age and former revascularisation were associated with an increased risk for MACCEs, while CABG appeared to...

In this large prospective cohort study, we found that ISSD, defined based on objective but not subjective sleep duration, is associated with increased risk of incident hypertension at a median follow-up duration of 5.1 years. In contrast, INSD, either defined based on objective or subjective sleep duration, is not associated with increased hypertension risk. These data further support that ISSD is a phenotype of insomnia disorder associated with new onset hypertension in adult women and men...