In this detailed retrospective cohort study, we observed no increased risk of clinically reported RIs among PAP therapy users relative to nonusers. Similarly, PAP adherence was not associated with a higher risk of RIs among PAP users. Our findings provide new evidence to suggest that PAP therapy is not a primary driver of RI risk. Our study, which included a larger sample of patients and longitudinal design to support assessment of temporality, supports these findings and provides additional...

These recommendations based on asymptomatic individuals highlight an important gap in sleep health awareness among both health care professionals and patients. Because the early symptoms of OSA tend to occur in sleep, when the person with the condition is less aware, there is a definite potential for underreporting. Hence, if the person with OSA is not fully aware of these symptoms it makes communicating them to their health care provider even harder. Gasping for air during the night, night...

Congenital central hypoventilation syndrome is a rare disorder due to a mutation in the PHOX2B gene, characterized by a failure in autonomic control of breathing with diminished or absent response to hypoxia and hypercapnia, which is most pronounced during sleep. Most patients present from birth with central apneas and hypoventilation, or later in the setting of a physiologic stress. Recent literature in mice with a Phox2b27Ala/+ mutation suggests a predisposition to obstructive apneas...