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Association of obstructive sleep apnea severity with the composition of the upper airway microbiome

In this study, the microbial composition of the upper airway mucosa was characterized in patients with OSA. Although there were no...

S-Med

Feb 251 min read

Management of REM sleep behavior disorder: an American Academy of Sleep Medicine clinical practice guideline

The behaviors of RBD widely vary from night to night and over time in the same individual and between patients. Contrary to the classic...

S-Med

Feb 202 min read

Recognition and Treatment of Sleep-Disordered Breathing in Obese Hospitalized Patients May Improve Survival. The HoSMed Database

In this analysis of a large database of hospitalized patients, we confirmed that there is a high prevalence of undiagnosed...

S-Med

Feb 181 min read

Insulin Resistance and Hypertension in Obese Youth With Sleep-Disordered Breathing Treated With Positive Airway Pressure: A Prospective Multi-center Study

Our study is the first long-term multi-center prospective cohort study to simultaneously evaluate metabolic and cardiovascular markers in...

S-Med

Feb 131 min read

Severity, comorbidities, and adherence to therapy in Native Hawaiians/Pacific Islanders with obstructive sleep apnea

This description of the disease severity of OSA among patients at a single academic center with a sizeable NHPI population shows 3 key...

S-Med

Feb 111 min read

Outcomes in coronary artery disease patients with sleepy obstructive sleep apnoea on CPAP

Nearly half of clinical populations with coronary artery disease (CAD) also have obstructive sleep apnoea (OSA) and these individuals...

S-Med

Feb 71 min read

Daily associations between modifiable sleep behaviors and night-time sleep among young adult drinkers with insomnia

We found empirical support for recommendations that young adult drinkers with insomnia prioritize a comfortable sleep environment, limit...

S-Med

Feb 52 min read

Diagnosis and management of sleep apnea by a clinical nurse: a non-inferiority randomized clinical trial

In this open-label randomized controlled trial we found that nurse-communicated management of uncomplicated OSA in the sleep clinic was...

S-Med

Jan 291 min read

Association between risk of obstructive sleep apnea and cognitive performance,frailty, and quality of life among older adults with atrial fibrillation

In this contemporary study of older adults with AF in whom risk for OSA was characterized systematically, we observed a high prevalence...

S-Med

Jan 231 min read

Improving performance on night shift: a study of resident sleep strategies

Night shift work is an unavoidable aspect of an internal medicine residency. Given the gravity of responsibility an internal medicine...

S-Med

Jan 212 min read

Is fluid overload a target to treat sleep disordered breathing in patients with end-stage renal disease, and what are the underlying mechanisms?

Sleep problems are more common in patients with renal failure compared to populations without overt severe comorbidities. Both central...

S-Med

Jan 171 min read

Effect of continuous positive airway pressure on blood pressure and metabolic profile in women with sleep apnoea

To the best of our knowledge, this is the first RCT to address the effect of CPAP therapy on the blood pressure values and metabolic...

S-Med

Jan 151 min read

Cardiovascular and metabolic effects of a mandibular advancement device and continuous positive airway pressure in moderate obstructive sleep apnea: a randomized controlled trial

This study showed that treatment of patients with moderate OSA with either MAD or CPAP therapy had no profound effect on major...

S-Med

Jan 101 min read

In patients with heart failure, enhanced ventilatory response to exercise is associated with severe obstructive sleep apnea

his is the first study to show that in patients with HFrEF, the VE/VCO 2 slope is associated with severe OSA. When patients with HF...

S-Med

Jan 71 min read

CPAP titration by an auto-CPAP device based on snoring detection: a clinical trial and economic considerations

Ideally, the nCPAP level required for the treatment of OSAS is determined by two sequential night studies, including one polysomnography...

S-Med

Jan 31 min read

Sex differences in Epworth Sleepiness Scale normalization with continuous positive airway pressure

The purpose of the present study was to assess whether the variables associated with improvement in the ESS in patients with OSA on CPAP...

S-Med

Dec 24, 20242 min read

The negative health effects of having a combination of snoring and insomnia

In this large-scale, population-based study, we found that a combination of self-reported snoring and insomnia symptoms has an effect on...

S-Med

Dec 17, 20241 min read

Intermittent hypoxia in obstructive sleep apnoea mediates insulin resistance through adipose tissue inflammation

In this report we provide evidence from cell culture, murine and human studies that IH in OSA contributes independently to the...

S-Med

Dec 10, 20242 min read

Adherence to continuous positive airway pressure reduces the risk of 30-day hospital re-admission among older adults with co-morbid obstructive sleep apnea and cardiovascular disease

In this national study of older adult Medicare beneficiaries with co-morbid OSA and CVD, high adherence to CPAP was associated with...

S-Med

Dec 6, 20241 min read

Association of cortical arousals with sleep-disordered breathing events

The AASM recommends scoring hypopneas in adults when there is a ≥ 3% oxygen de-saturation or when the event is associated with an...

S-Med

Dec 3, 20241 min read