Influence of apnea vs hypopnea predominance in predicting mean therapeutic positive airway pressures among patients with obstructive sleep apnea
- S-Med
- Apr 11
- 1 min read
This study is the first to characterize OSA severity using therapeutic PAP levels obtained from an aPAP device and to compare apnea vs hypopnea predominance in a therapeutic context. The results show that apnea-predominant patients have minimally higher PAP levels than hypopnea-predominant patients. Other notable differences between groups include: greater male percentage, greater BMI, and greater overall AHI in the apnea predominant group. Possible interactions explaining these differences include sex differences in OSA, with women having lower AHI and greater BMI compared to men, which could contribute to sex, AHI, and BMI differences observed between apnea and hypopnea-predominant groups. These findings highlight the complex nature of OSA physiology with multiple factors influencing diseases characteristics and emphasize the need for a multivariable approach to modeling these relationships.
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