No study to date has examined how nightmares affect treatment retention and treatment course of cognitive behavioural therapy for insomnia (CBT-I). To fill this gap, this study examined whether nightmares predicted treatment dropout or treatment response to CBT-I. Our results indicate that nightmares predict treatment dropout. This finding has clinical relevance as it indicates that, when using CBT-I, one should screen for and consider nightmares in order to reduce treatment attrition and...

In-laboratory polysomnography for hypoglossal nerve stimulator titration has not previously been compared to patient-controlled, home-based device adjustment centered on subjective sleep experience to evaluate whether patients experience similar improvements in objective and subjective outcomes for obstructive sleep apnea. This prospective, multicenter, randomized clinical trial randomly assigned patients to 1 of 2 management pathways to evaluate whether patients experienced similar outcomes....

Current Knowledge/Study Rationale: Point-of-care, quick, non-invasive biomarkers of autonomic arousal may have value for the purpose of subtyping those persons with insomnia who exhibit physiologic hyperarousal. Persons with hyperarousal may show differential response to cognitive behavioural therapy for insomnia vs hypnotic medications. We found that autonomic nervous system assays differ between persons with no vs modest insomnia symptoms, and there was a high degree of correlation between...