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The treatment of mild OSA with CPAP or mandibular advancement device and the effect on blood pressure and endothelial function after one year of treatment

CPAP or MAD treatment for individuals with mild OSA did not improve BP parameters and overall PAT variables after 6 months and 1 year in the total sample. However, AIx adjusted to 75 beats per minute presented a significant trend toward improvement, decreasing in both entire effective-treatment groups, with a low effect size; diastolic BP dipping decreased between 6 months and 12 months in the effective treatment CPAP group but also with a low effect size.

CPAP and MAD were more effective than control, and CPAP was more effective than MAD for most polysomnographic parameters. In the control group, there was no increase in OSA after 12 months in terms of polysomnographic results. MAD had higher adherence than CPAP in terms of the average hours of use of treatment per day, as well as in respect to the number of patients who adhered to the treatment compared to

CPAP. Our results are similar to the previous literature in regard to OSA in general.



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