The prevalence of sleep-disordered breathing and associated risk factors in patients with de-compensated congestive heart failure in Mozambique
- S-Med
- Aug 8
- 2 min read
To our knowledge, this is the first study conducted to evaluate the prevalence of SDB in patients with CHF in the sub-Saharan Africa community. Based on the analysis of our study participants, the overall prevalence of SDB in patients with de-compensated CHF was 72%, with 46% of them having CSR. Being of male sex and having a higher BMI and lower LVEF were significantly associated with a higher likelihood of SDB. In addition, being of male sex and having a lower ejection fraction and a larger left atrial size were associated with increased probability of CSR. The study’s findings add to the current body of literature regarding SDB breathing in patients with de-compensated CHF, primarily addressing a gap of research present in the Mozambique population. In the study participants, the proportion of SDB in patients with CHF was over 70%. This percentage is comparable to values observed in North America but it was higher than anticipated, given the lack of substantial obesity, the younger age of the participants, and other major risk factors in this population. In addition, there was a high prevalence of Cheyne–Stokes breathing in patients with de-compensated CHF, even though this breathing pattern is generally uncommon in females and young adults. Our results likely reflect the high severity of heart failure in this population and might reflect the observed heart failure etiologies and medical heart failure therapies available for use. Studying differences across populations is important because the etiology of CHF conditions appears to vary by country (eg, coronary artery disease, which is one possible condition of CHF, is relatively uncommon in sub-Saharan Africa) .In contrast, other diseases that may be related to CHF, such as HIV, rheumatic heart disease, hypertensive heart disease, peripartum cardiomyopathy, and idiopathic dilated cardiomyopathy, are quite common in Mozambique. Many of these sub-Saharan African patients are fairly lean and young; thus, their respiratory function (eg, SDB), a possible indicator of CHF, is predicted to be quite different from that of patients with CHF in the United States or other well-resourced countries
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