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The prevalence and comorbidities of obstructive sleep apnea in middle-aged men and women: the Busselton Healthy Ageing Study

This study of males and females born between 1946 and 1964 from a predominantly White population has shown that OSA is a substantial public health problem, the prevalence of which appears to be increasing relative to previous estimates drawn from the same community. The prevalence of any OSA (AHI ≥ 5 events/h) in the present study was very high in both males and females, and in males moderate-severe OSA had increased 4- to 5-fold over a 20-year period. Moderate-severe OSA has also increased in females compared with previous studies in other populations. This study found no significant increase in the prevalence of OSA since 2007. Features associated with OSA remain age and body weight in both men and women and alcohol consumption in men. OSA was associated with depression (increased odds) in males and skin cancer and depression (decreased odds) in females. Symptomatic OSA was common and associated with increased sleepiness when driving.

This study was undertaken over a 5-year period, commencing in 2010, in males and females born between 1946 and 1964, so that participants were between 46 and 69 years of age at the time of study. The aim of the Busselton Healthy Ageing Study was to

estimate the prevalence of multi-morbidity and its effects on physical and cognitive function in a middle-aged general population. The response rate from all potentially eligible participants (all those on the electoral roll—voting is compulsory in Australia) was high at 62%. The study population is predominantly White with no Aboriginal participants and few Asian participants (<1%). The estimation of the prevalence of OSA and OSA syndrome was similar in participants of the BHAS who did or did not (imputed prevalence) undertake the home sleep study.


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