Insomnia with objective, but not subjective, short sleep duration is associated with increased risk of incident hypertension: the Sleep Heart Health Study
- S-Med
- 2 days ago
- 2 min read
In this large prospective cohort study, we found that ISSD, defined based on objective but not subjective sleep duration, is associated with increased risk of incident hypertension at a median follow-up duration of 5.1 years. In contrast, INSD, either defined based on objective or subjective sleep duration, is not associated with increased hypertension risk. These data further support that ISSD is a phenotype of insomnia disorder associated with new onset hypertension in adult women and men and, thus,
more severe from a cardiometabolic standpoint.
Our study is consistent with the study by Fernandez-Mendoza et al in the Penn State Adult Cohort who first reported that ISSD, defined based on 1 night of in-lab PSG, was associated with increased risk for incident hypertension, defined based on self-reports of a physician diagnosis of hypertension at follow-up. The current study had a larger sample size and used a definition of incident hypertension by including 3 consecutive manually obtained measures of BP and/or use of antihypertensive medications to define incident hypertension, and the findings were consistent with Fernandez-Mendoza et al Our study is also consistent with a prior study by Bertisch et a in the SHHS who showed that ISSD was associated with increased risk of cardiovascular diseases. Notably, our study failed to show an association between ISSD defined based on self-reported sleep duration and incident hypertension, consistent with a cross-sectional previous study in a clinical sample. The consistent findings based on 2 large general population cohort studies, ie, the PASC and the SHHS, on the association of ISSD with cardiovascular morbidity further support the concept that it is a more severe, objectively defined phenotype associated with increased risk of cardiometabolic morbidity and mortality.
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