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Dysphagia severity is associated with worse sleep-disordered breathing in infants with Down syndrome
This study demonstrates that there is a high prevalence of dysphagia and SDB in I-DS. Furthermore, we demonstrated our hypothesis that...

S-Med
May 221 min read


Electronic health record–derived outcomes in obstructive sleep apnea managed with positive airway pressure tracking systems
This study characterizes changes in certain EHR-derived outcomes within 1 year of CPAP therapy guided by adherence and AHI flow tracking...

S-Med
May 201 min read


Assessment of continuous positive airway pressure effect on the circadian clock signaling pathway in obstructive sleep apnea patients
Circadian clock disruption, represented by alteration of the particular set of genes – CLOCK, CRY1, BMAL1, PER1 – can be one of the OSA...

S-Med
May 152 min read


Co-morbid parasomnias in narcolepsy and idiopathic hypersomnia: more REM than NREM parasomnias
In this large, controlled group of adult patients with well-defined NT1, NT2, and IH, current co-morbid NREM parasomnias were as rare as...

S-Med
May 132 min read


Does total sleep time substantially increase after cognitive behavioral therapy for insomnia?
The findings of the current study indicate that the reported average of an approximately 45-minute gain in self-reported TST after CBT-I...

S-Med
May 92 min read


Circulating C-reactive protein levels in patients with suspected obstructive sleep apnea
BMI, AHI, and female sex were independent predictors of CRP in this cohort of patients with suspected OSA. In addition, multiple measures...

S-Med
May 71 min read


A randomized controlled trial of cognitive behavioral therapy for insomnia and PAP for obstructive sleep apnea and co-morbid insomnia: effects on nocturnal sleep and daytime performance
The goal of this study was to provide further insights into the clinical impact of using CBT-I and PAP on nocturnal sleep and daytime...

S-Med
Apr 242 min read
The impact of different CPAP delivery approaches on nightly adherence and discontinuation rate in patients with obstructive sleep apnea
Two findings in this study were of note. First, that adherence with PAP was less in both groups receiving direct home shipments of PAP...

S-Med
Apr 222 min read


CPAP titration by an auto-CPAP device based on snoring detection:a clinical trial and economic considerations
Ideally, the nCPAP level required for the treatment of OSAS is determined by two sequential night studies, including one polysomnography...

S-Med
Apr 161 min read


Influence of apnea vs hypopnea predominance in predicting mean therapeutic positive airway pressures among patients with obstructive sleep apnea
This study is the first to characterize OSA severity using therapeutic PAP levels obtained from an aPAP device and to compare apnea vs...

S-Med
Apr 111 min read


Congenital central hypoventilation syndrome without hypoventilation: is it congenital central hypoventilation syndrome?
We describe 3 family members with PHOX2B gene deletion across 2 generations that experienced some of the known complications of CCHS yet...

S-Med
Apr 82 min read


The differential impact of respiratory event scoring criteria on CPAP eligibility in women and men
Utilizing different hypopnea scoring criteria to define OSA has been shown to significantly impact the prevalence and severity...

S-Med
Apr 21 min read


Impact of patient and family engagement in improving continuous positive airway pressure adherence in patients with obstructive sleep apnea: a randomized controlled trial
In this RCT, the use of PAP declined at 6 months in the control group but was retained in the intervention group. These findings of the...

S-Med
Mar 271 min read


Clinical Guidelines for the Manual Titration of Positive Airway Pressure in Patients with Obstructive Sleep Apnea
Positive airway pressure (PAP) devices are used to treat patients with sleep related breathing disorders (SRBDs), including obstructive...

S-Med
Mar 251 min read


Association of alternative polysomnographic features with patient outcomes in obstructive sleep apnea: a systematic review
In this comprehensive systematic review, we identified 31 studies that identified promising alternative PSG metrics that have the...

S-Med
Mar 201 min read


A pilot randomized trial comparing CPAP vs bilevel PAP spontaneous mode in the treatment of hypoventilation disorder in patients with obesity and obstructive airway disease
To our knowledge, this is the first randomized controlled trial that compares PAP therapies in patients with chronic hypercapnic...

S-Med
Mar 181 min read


Effectiveness of current digital cognitive behavioural therapy for insomnia interventions for adolescents with insomnia symptoms: A systematic review and meta-analysis
This systematic review and meta-analysis advances understanding of the effectiveness and acceptability of digital sleep interventions in...

S-Med
Mar 141 min read


High-quality and anti-inflammatory diets and a healthy lifestyle are associated with lower sleep apnea risk
This large community-based study shows that, irrespective of caloric intake, higher overall dietary quality and an anti-inflammatory diet...

S-Med
Mar 121 min read


Development of a physiological-based model that uses standard polysomnography and clinical data to predict oral appliance treatment outcomes in obstructive sleep apnea
The main findings of this study are that a machine learning–based model underpinned by OSA endotype concepts that includes routinely...

S-Med
Mar 71 min read


Clinical Guideline for the Evaluation and Management of Chronic Insomnia in Adults
“Insomnia” has been used in different contexts to refer to either a symptom or a specific disorder. In this guideline, an insomnia...

S-Med
Mar 52 min read
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